An aminoglycoside antimicrobial medicine is used to prevent or treat a variety of serious bacterial infections. An effective agent against a broad spectrum of organisms including Pseudomonas aeruginosa. (Brewer, 1977) The first drug of choice in the treatment of serious infections due to gram-negative bacilli. (R S Edson, 1983) An essential antibiotic used against numerous infections caused by multidrug-resistant strains. (Tolmasky, 2017) An alternative treatment of infections due to gram-negative bacilli. (J F Acar, 1976) An important addition to the antibiotic armamentarium of a hospital with high gentamicin or tobramycin resistance. (F D Pien, 1981) An efficacious and safe antibiotic in the treatment of severe gram-negative infections in elderly patients. (M Vanhaeverbeek, 1993) Significantly more efficacious than netilmicin for the treatment of Pseudomonas aeruginosa infections. (M Noone, 1989) The preferred agent for serious nosocomial infections caused by gram-negative bacilli. (UIS S. GONZALEZ III, 1998) More effective against extended-spectrum β-lactamase-producing E. coli and quinolone-resistant E. coli than other aminoglycosides. (Sung-Yeon Cho, 2016)